BDBM50050527 Boronic acid derivative::CHEMBL66032::US11096924, DASH-inhibitors 5466::US11559537, Compound 5466

SMILES CC[C@H](N)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=PHCFSFBQEROREL-BQBZGAKWSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050527   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM50050527(Boronic acid derivative | CHEMBL66032 | US11096924...)
Affinity DataIC50:  23nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM50050527(Boronic acid derivative | CHEMBL66032 | US11096924...)
Affinity DataIC50:  2.30E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In DepthDetails US Patent